Glutathione plays a very important role to fight against oxidative stress. It is said that rigorous exercise can increase the intensity of oxidative stress and also the production of free radicals inside our cells. For proper functioning of your cells and the DNA integrity, it is vital to have proper regulation of the cellular balance i.e. between oxidation and anti-oxidation. There are various diseases like Cancer, Parkinson’s disease and Alzheimer’s disease are all because of the redox state of cells.
In such cases, many antioxidants are prescribed to minimize the level of oxidative stress and this includes supplements like Glutathione and N-Acetylcysteine. These supplements do have the ability to reduce oxidative stress and negate all the ill effects caused by oxidative stress. You can buy these medicines from the S M Pharmaceuticals Co. Ltd. which makes different drugs of the highest quality to improve the life of Thai people.
Glutathione (กรู ตา ไธ โอน, term in Thai) is well-known for its property to reduce the lipid peroxidation of the cellular membranes and many other similar targets which are caused due to oxidative stress. On the other hand, N-acetylcysteine is a by-product of this glutathione. It produces cysteine residue which plays a major role in the maintenance and metabolism of glutathione.
About reactive oxygen species and oxidative stress:
As we all know the presence of oxygen is found in every cell membrane. However, if there comes a situation where the oxygen level goes down or there is an overconsumption of oxygen then this can lead to the production of free radicals. It is often called the reactive oxygen species.
Glutathione’s working as An Antioxidant:
This is one of the most studied antioxidants. It is said to be grown chemically throughout our body or is present in every cell of our body in a very higher concentration. Looking at its positive aspects, it is used a lot to work as antioxidant defense, detoxification of xenobiotics, storage and transport of cysteine, regulation of immune response, and many more. Thus, it helps to maintain the redox state of the cell.
Glutathione’s response to exercise:
During the intense exercises, there is an increase in lipid proliferation which happens due to oxidative stress. Therefore, during this time, there is an increase in the amount of blood of oxidized glutathione, which in turn increases the oxidative stress in the person. A decreased level of glutathione is mainly because there is an increase in their utilization inside the muscles mainly because they fight against free radicals.
About N-Acetyl-Cysteine:
This is a residue of acetylated cysteine. An optimal thiol redox state is very important in case you want to make use of this protective ability of the cell against oxidative stress. For this when you need the glutathione available in your cell, you need to maintain the presence of cysteine in the blood. On the other hand, optimal usage of this cysteine needs to be achieved in case we want to maintain the biosynthesis of reduced glutathione.
In conclusion, it is important to have the development of free radicals as well as oxidative stress during exercise time. It helps to maintain the performance, overall health, and recovery of the person. Although a relationship between oxidative stress and exercise still needs study to be done.
